PAG neuronal NMDARs activation mediated morphine-induced hyperalgesia by HMGB1-TLR4 dependent microglial inflammation
Jingjing Mo, Zijing Lu, Jialing Peng, Xiang-pen Li, Lihuan Lan, Hongxuan Wang, Ying Peng, Ying Peng
Topics & Concepts
MicrogliaTLR4Proinflammatory cytokineHMGB1NeuroinflammationPharmacologyInflammationReceptorMorphineChemistryMedicineInternal medicineBiochemistryNeuroinflammation and Neurodegeneration MechanismsPain Mechanisms and TreatmentsNeuropeptides and Animal Physiology