In-depth molecular profiling of an intronic GNAO1 mutant as the basis for personalized high-throughput drug screening
Alexey Koval, Yonika Arum Larasati, Mikhail Savitsky, Gonzalo P. Solis, Jean‐Marc Good, Mathieu Quinodoz, Carlo Rivolta, Andrea Superti‐Furga, Vladimir L. Katanaev
Topics & Concepts
Missense mutationMutantDrug discoveryComputational biologyBiologyGeneticsG protein-coupled receptorMutationGeneBioinformaticsReceptorGenomics and Rare DiseasesBiomedical Text Mining and OntologiesReceptor Mechanisms and Signaling