A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer’s disease
Yongjin Yoo, Gernot Neumayer, Yohei Shibuya, Marius Marc-Daniel Mader, Marius Wernig
Topics & Concepts
TREM2MicrogliaBiologyDiseaseNeuroscienceTransplantationGenetic enhancementLoss functionPathogenesisFunction (biology)ImmunologyGeneInflammationCell biologyMedicineGeneticsPhenotypePathologyInternal medicineNeuroinflammation and Neurodegeneration MechanismsInflammation biomarkers and pathwaysImmune cells in cancer