Osmium(<scp>ii</scp>) tethered half-sandwich complexes: pH-dependent aqueous speciation and transfer hydrogenation in cells
Sonia Infante-Tadeo, Vanessa Rodríguez‐Fanjul, Abraha Habtemariam, Ana M. Pizarro
Abstract
(XY = 4-Me-picolinate) with formate has been quantified inside MDA-MB-231 and MCF7 breast cancer cells. The tether Os-arene complexes presented here can be exploited for the intracellular conversion of metabolites that are essential in the intricate metabolism of the cancer cell.
Topics & Concepts
OsmiumChemistryAqueous solutionAquationAqueous mediumTransfer hydrogenationCatalysisCombinatorial chemistryRutheniumOrganic chemistryKineticsReaction rate constantPhysicsQuantum mechanicsMetal-Organic Frameworks: Synthesis and ApplicationsAsymmetric Hydrogenation and CatalysisMetal complexes synthesis and properties