Iontophoresis-mediated direct delivery of nucleic acid therapeutics, without use of carriers, to internal organs via non-blood circulatory pathways
Mahadi Hasan, Tatsuya Fukuta, Shinya Inoue, H Mori, Mayuko Kagawa, Kentaro Kogure
Topics & Concepts
Nucleic acidTransdermalEndocytosisDrug carrierSmall interfering RNADrug deliverySystemic administrationPharmacologyChemistryIontophoresisCell biologyBiologyDrugTransfectionBiochemistryCellIn vivoNeuroscienceGeneBiotechnologyOrganic chemistryMicrofluidic and Bio-sensing TechnologiesMicrobial Inactivation MethodsLipid Membrane Structure and Behavior