RBMS3, a downstream target of AMPK, Exerts Inhibitory Effects on Invasion and Metastasis of Lung Cancer
Shi-Lin Lv, Xu Zhou, Yuanjun Li, Lingyu Luo, Deqiang Huang
Abstract
Our study highlights a novel mechanism by which LKB1/AMPK pathway activation inhibits lung cancer invasion and metastasis by promoting RBMS3 expression, offering insights in developing innovative lung cancer therapies.
Topics & Concepts
Lung cancerMetastasisCarcinogenesisCancer researchAMPKEpithelial–mesenchymal transitionImmunohistochemistryCancerBiologyMedicineProtein kinase AInternal medicineKinaseCell biologyRNA modifications and cancerCancer-related molecular mechanisms researchRNA Research and Splicing