Acidity-responsive nanoplatforms aggravate tumor hypoxia via multiple pathways for amplified chemotherapy
Jiajia Yin, Chenxi Wang, Леи Жао, Kang Xu, Yuxin Guo, Xuejiao Song, Jinjun Shao, Huae Xu, Xiaochen Dong, Xiaochen Dong
Topics & Concepts
Hypoxia (environmental)Tumor microenvironmentTumor hypoxiaCancer researchTirapazaminePhotodynamic therapyProdrugChemotherapyNanocarriersIn vivoPhotosensitizerEmbolizationMetastasisRadiation therapyPharmacologyMaterials scienceMedicineChemistryBiologyCancerDrugOxygenSurgeryInternal medicineBiochemistryTumor cellsIn vitroCytotoxicityBiotechnologyOrganic chemistryNanoplatforms for cancer theranosticsCancer, Hypoxia, and MetabolismCancer Research and Treatments