Anti-inflammatory effect and inhibition of nitric oxide production by targeting COXs and iNOS enzymes with the 1,2-diphenylbenzimidazole pharmacophore
Mónica I. García-Aranda, Jazmin E. González-Padilla, Carlos Z. Gómez‐Castro, Yolanda M. Gómez-Gómez, Martha Cecilia Rosales‐Hernández, Efrén V. Garcı́a-Báez, Marina Olivia Franco-Hernández, José Luis Castrejón-Flores, Itzia I. Padilla‐Martínez
Topics & Concepts
ChemistryPharmacophoreIn vivoNitric oxidePharmacologyNitric oxide synthaseAcetamideEnzymeIn silicoCyclooxygenaseIn vitroInflammationBiochemistryStereochemistryImmunologyMedicineBiotechnologyBiologyGeneOrganic chemistryInflammatory mediators and NSAID effectsSynthesis and biological activitySynthesis and Reactions of Organic Compounds