Artificial nucleotide codons for enzymatic DNA synthesis
Nazarii Sabat, Andreas Stämpfli, Marie Flamme, Steven P. Hanlon, Serena Bisagni, Filippo Sladojevich, Kurt Püntener, Marcel Hollenstein
Abstract
Synthesis three-by-three: trinucleotide triphosphates can be used for enzymatic DNA synthesis provided their backbone is stabilized with chemical modifications.
Topics & Concepts
NucleotideDNAEnzymeDNA synthesisChemistryBiochemistryCombinatorial chemistryGeneDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniquesRNA and protein synthesis mechanisms