Molecular crowding promotes the aggregation of parallel structured G-quadruplexes
Chao Gao, Jieya Deng, Naureen Anwar, Muhammad Umer, Jixin Chen, Qiao Wu, Xingxing Dong, Hua Xu, Yi He, Zhangqian Wang
Topics & Concepts
Förster resonance energy transferG-quadruplexAntiparallel (mathematics)Circular dichroismChemistryOligonucleotideMolecular modelBiophysicsMonomerMolecular dynamicsCrowdingMicroscale thermophoresisGel electrophoresisCrystallographyStereochemistryDNABiochemistryFluorescenceBiologyPolymerComputational chemistryNeuroscienceMagnetic fieldQuantum mechanicsOrganic chemistryPhysicsDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery