Litcius/Paper detail

UV Inactivation of SARS-CoV-2 across the UVC Spectrum: KrCl* Excimer, Mercury-Vapor, and Light-Emitting-Diode (LED) Sources

Ben Ma, Patricia M. Gundy, Charles P. Gerba, Mark D. Sobsey, Karl G. Linden

2021Applied and Environmental Microbiology155 citationsDOIOpen Access PDF

Abstract

UV light is an effective tool to help stem the spread of respiratory viruses and protect public health in commercial, public, transportation, and health care settings. For effective use of UV, there is a need to determine the efficiency of different UV wavelengths in killing pathogens, specifically SARS-CoV-2, to support efforts to control the ongoing COVID-19 global pandemic and future coronavirus-caused respiratory virus pandemics. We found that SARS-CoV-2 can be inactivated effectively using a broad range of UVC wavelengths, and 222 nm provided the best disinfection performance. Interestingly, 222-nm irradiation has been found to be safe for human exposure up to thresholds that are beyond those effective for inactivating viruses. Therefore, applying UV light from KrCl* excimers in public spaces can effectively help reduce viral aerosol or surface-based transmissions.

Topics & Concepts

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Virus inactivationCoronavirus disease 2019 (COVID-19)Mercury (programming language)ChemistryPhotochemistryOptoelectronicsVirusVirologyMaterials scienceMedicineComputer scienceInfectious disease (medical specialty)PathologyDiseaseProgramming languageInfection Control and VentilationCOVID-19 impact on air qualitySARS-CoV-2 detection and testing