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Experimental and Modeling Evidence Supporting the Trans-Inhibition Mechanism for Preincubation Time-Dependent, Long-Lasting Inhibition of Organic Anion Transporting Polypeptide 1B1 by Cyclosporine A

Saki Izumi, Yoshitane Nozaki, Wooin Lee, Yuichi Sugiyama

2022Drug Metabolism and Disposition20 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryMechanism (biology)StereochemistryOrganic anion-transporting polypeptideBiochemistryPharmacologyBiologyGeneTransporterEpistemologyPhilosophyDrug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesPregnancy and Medication Impact
Experimental and Modeling Evidence Supporting the Trans-Inhibition Mechanism for Preincubation Time-Dependent, Long-Lasting Inhibition of Organic Anion Transporting Polypeptide 1B1 by Cyclosporine A | Litcius