Design, synthesis and biological evaluation of novel carboline-cinnamic acid hybrids as multifunctional agents for treatment of Alzheimer’s disease
Qinghong Liao, Qi Li, Yifan Zhao, Pan Jiang, Yuhui Yan, Haopeng Sun, Wenyuan Liu, Feng Feng, Wei Qu
Topics & Concepts
ChemistryCinnamic acidToxicityNeurotoxicityNeuroprotectionIn vivoInhibitory postsynaptic potentialPharmacologyBiochemistryNeuroscienceBiologyOrganic chemistryBiotechnologySynthesis and bioactivity of alkaloidsCholinesterase and Neurodegenerative DiseasesCancer therapeutics and mechanisms