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Recent progress in the rational design and applications of nanozymes

Yutian Zhang, Qi Zhao, Min Zhang, Na Na, Jin Ouyang, Xiaotong Shen

2025Biomedical Analysis13 citationsDOIOpen Access PDF

Abstract

In order to overcome the limitations of natural enzymes, nanomaterials with enzyme-like activity, commonly named as nanozymes, have been widely studied in the past few decades. Due to their distinctive properties, nanozymes have the potential to expand the applications of natural enzymes. However, a significant number of nanozymes have been obtained through trial-and-error methods, indicating the necessity for a rational design in nanozymes. In this review, several types of representative nanozymes are introduced. Importantly, the rational design strategies of nanozymes are emphasized, along with the introduction of their corresponding applications. Additionally, the obstacles and prospects of nanozyme researches are outlined.

Topics & Concepts

Computer scienceRational designNanotechnologyBiochemical engineeringManagement scienceEngineeringMaterials scienceAdvanced Nanomaterials in CatalysisNanocluster Synthesis and ApplicationsAdvanced biosensing and bioanalysis techniques