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CircPDIA3/miR-449a/XBP1 feedback loop curbs pyroptosis by inhibiting palmitoylation of the GSDME-C domain to induce chemoresistance of colorectal cancer

Jiatong Lin, Zejian Lyu, Huolun Feng, Huajie Xie, Jingwen Peng, Weifu Zhang, Jun Zheng, Jiabin Zheng, Zihao Pan, Yong Li

2024Drug Resistance Updates44 citationsDOI

Topics & Concepts

PyroptosisCancer researchColorectal cancerPalmitoylationGene knockdownIn vivoBiologyChemistryCancerCell biologyApoptosisProgrammed cell deathGeneticsBiochemistryEnzymeCysteineCircular RNAs in diseasesInflammasome and immune disordersCancer-related molecular mechanisms research
CircPDIA3/miR-449a/XBP1 feedback loop curbs pyroptosis by inhibiting palmitoylation of the GSDME-C domain to induce chemoresistance of colorectal cancer | Litcius