RORγt agonist synergizes with CTLA-4 antibody to inhibit tumor growth through inhibition of Treg cells via TGF-β signaling in cancer
Enming Tian, Mingcheng Yu, Mei Feng, Lixue Lu, Chenglong Liu, Lian Shen, Yonghui Wang, Qiong Xie, Di Zhu
Topics & Concepts
C-C chemokine receptor type 6Cytotoxic T cellCancer researchRAR-related orphan receptor gammaTumor microenvironmentChemokine receptorBiologyCell biologyFOXP3ChemistryChemokineImmune systemImmunologyIn vitroBiochemistryPsoriasis: Treatment and PathogenesisCancer Immunotherapy and BiomarkersT-cell and B-cell Immunology