Evolution of Ribosomal Protein S14 Demonstrated by the Reconstruction of Chimeric Ribosomes in Bacillus subtilis
Genki Akanuma, Fujio Kawamura, Satoru Watanabe, Masaki Watanabe, Fumiya Okawa, Yousuke Natori, Hideaki Nanamiya, Kei Asai, Taku Chibazakura, Hirofumi Yoshikawa, Akiko Soma, Takashi Hishida, Yasuyuki Kato‐Yamada
Abstract
S14, an essential ribosomal protein, may have evolved to adapt bacteria to zinc-limited environments by replacement of a zinc-binding motif with a zinc-independent sequence. It was expected that the bacterial ribosome would be tolerant to replacement of S14 because of the previous prediction that the spread of C− type S14 involved horizontal gene transfer.
Topics & Concepts
Bacillus subtilisBiologyRibosomeRibosomal proteinHeterologousRibosomal RNA50SMutantEscherichia coli30SPolysomeEukaryotic Large Ribosomal SubunitMolecular biologyProtein subunitEukaryotic RibosomeBiochemistryGeneticsBacteriaRNAGeneRNA and protein synthesis mechanismsRNA modifications and cancerBacterial Genetics and Biotechnology