VEGFC ameliorates salt-sensitive hypertension and hypertensive nephropathy by inhibiting NLRP3 inflammasome via activating VEGFR3-AMPK dependent autophagy pathway
Qiuwen Wu, Wei Meng, Bin Zhu, Xi Chen, Jiaxin Fu, Chunyu Zhao, Gang Liu, Xing Luo, Ying Lv, Wenqi Zhao, Fan Wang, Sining Hu, Shuo Zhang
Topics & Concepts
AMPKAutophagyInflammasomeDownregulation and upregulationKidneyInternal medicineEndocrinologyChemistryInflammationPharmacologyMedicineCell biologyProtein kinase ACancer researchPhosphorylationBiologyBiochemistryApoptosisGeneInflammasome and immune disordersHydrogen's biological and therapeutic effectsAutophagy in Disease and Therapy