A gold nanoparticle engineered metal–organic framework nanoreactor for combined ferroptosis and mild photothermal therapy
Ruyue Wei, Yanhua Li, Peng Gao, Xia Zhang, Xiaoyu Li, Kaixian Wang, Wei Pan, Na Li, Bo Tang
Abstract
We demonstrate a gold nanoparticle engineered metal-organic framework nanoreactor with photothermal, glucose oxidase-like and GSH-consuming performance to achieve the accumulation of hydroxyl radicals and the enhancement of the thermal sensitivity for combined ferroptosis and mild photothermal therapy.
Topics & Concepts
NanoreactorPhotothermal therapyNanoparticleColloidal goldNanotechnologyMaterials scienceMetal-organic frameworkChemistryOrganic chemistryAdsorptionNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisExtracellular vesicles in disease