Transcutaneous auricular vagal nerve stimulation improves functional dyspepsia by enhancing vagal efferent activity
Ying Zhu, Feng Xu, Dewen Lu, Peijing Rong, Jiafei Cheng, Miaomiao Li, Yaoyao Gong, Chao Sun, Wei Wei, Lin Lin, Jiande D. Z. Chen
2021American Journal of Physiology-Gastrointestinal and Liver Physiology99 citationsDOIOpen Access PDF
Abstract
Treatment of functional dyspepsia is difficult due to various pathophysiological factors. The proposed method of transcutaneous auricular vagal nerve stimulation improves symptoms of both dyspepsia and depression/anxiety, and gastric functions (accommodation and slow waves), possibly mediated via the enhancement of vagal efferent activity. This noninvasive and easy-to-implement neuromodulation method will be well received by patients and healthcare providers.
Topics & Concepts
MedicineEfferentInternal medicineVagal toneVagus nerveDepression (economics)ElectrogastrogramStimulationVagus nerve stimulationHeart rate variabilityEndocrinologyAnxietyAnesthesiaGastroenterologyStomachHeart rateAfferentBlood pressureMacroeconomicsPsychiatryEconomicsGastrointestinal motility and disordersVagus Nerve Stimulation ResearchPhonocardiography and Auscultation Techniques