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"Turn-on" aptamer-immune lateral flow assays for the detection of small molecule targets based on CHA-assisted and CRISPR/Cas12a mediated signal transduction and amplification

Haowei Dong, Yifei Qin, Pengwei Zhang, Liwen Lv, Chunlei Yu, Peng Jia, Jicheng Zhao, Fangling Du, Yemin Guo, Xia Sun

2025Biosensors and Bioelectronics20 citationsDOI

Topics & Concepts

AptamerCRISPRImmune systemComputational biologySignal transductionTransduction (biophysics)BiologyCell biologyChemistryMolecular biologyGeneticsBiophysicsGeneAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringBiosensors and Analytical Detection
"Turn-on" aptamer-immune lateral flow assays for the detection of small molecule targets based on CHA-assisted and CRISPR/Cas12a mediated signal transduction and amplification | Litcius