The Bcr-Abl inhibitor GNF-7 inhibits necroptosis and ameliorates acute kidney injury by targeting RIPK1 and RIPK3 kinases
Xia Qin, Longmiao Hu, Shen-Nan Shi, Xiaofei Chen, Chunlin Zhuang, Wen Zhang, Siriporn Jitkaew, Xiufeng Pang, Jianqiang Yu, Yexiong Tan, Hongyang Wang, Zhenyu Cai
Topics & Concepts
NecroptosisRIPK1Programmed cell deathKinaseCancer researchApoptosisAcute kidney injuryNecrosisPharmacologyBiologyCell biologyMedicineInternal medicineBiochemistryCell death mechanisms and regulationCarcinogens and Genotoxicity AssessmentDrug-Induced Hepatotoxicity and Protection