Rhodium-Catalyzed Chemoselective Hydrosilylation of Nitriles to an Imine Oxidation Level Enabled by a Pincer-type Group 13 Metallylene Ligand
Jun Takaya, Koki Ogawa, Ryota Nakaya, Nobuharu Iwasawa
Abstract
Syntheses and catalytic application of rhodium complexes having a pincer-type group 13 metallylene ligand are reported. The PGaIP–Rh complex exhibited high chemoselectivity for hydrosilylation of nitriles to an imine oxidation level, realizing efficient synthesis of oximes from nitriles with good functional group compatibility. A rhodium monohydride complex stabilized with PPh3 was synthesized and structurally characterized as a derivative of a plausible rhodium hydride intermediate.
Topics & Concepts
RhodiumHydrosilylationChemoselectivityChemistryPincer ligandPincer movementImineCatalysisLigand (biochemistry)HydrideMedicinal chemistryOrganic chemistryCombinatorial chemistryDerivative (finance)MetalReceptorEconomicsBiochemistryFinancial economicsOrganoboron and organosilicon chemistryAsymmetric Hydrogenation and CatalysisN-Heterocyclic Carbenes in Organic and Inorganic Chemistry