PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Müller cells during diabetic retinopathy
Yang Guo, Xiaomin Cang, Linling Zhu, Manhui Zhu, Aihong Li, Zhenzhen Wang, Yuting Zhang, Xueqin Wang, E Song
Topics & Concepts
mTORC1Glutamine synthetaseDownregulation and upregulationNeuroprotectionChemistryEndocrinologyInternal medicineBiologyGlutamineCell biologyPI3K/AKT/mTOR pathwayBiochemistrySignal transductionMedicineGeneAmino acidHippo pathway signaling and YAP/TAZUbiquitin and proteasome pathwaysCellular transport and secretion