Copper-catalyzed four-component reaction of alkenes, Togni's reagent, amines and CO<sub>2</sub>: stereoselective synthesis of (<i>Z</i>)-enol carbamates
Lu Wang, Pan Wang, Tianzuo Guo, Wenfang Xiong, Bangxiong Kang, Chaorong Qi, Gen Luo, Yi Luo, Huanfeng Jiang
Abstract
A copper-catalyzed four-component reaction of alkenes, Togni's reagent, amines and CO<sub>2</sub>was disclosed, providing an efficient and straightforward access to a range of stereodefined (<italic>Z</italic>)-enol carbamates.
Topics & Concepts
ChemistryReagentEnolCatalysisStereoselectivityCopperComponent (thermodynamics)Combinatorial chemistryMedicinal chemistryOrganic chemistryPhysicsThermodynamicsCarbon dioxide utilization in catalysisAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization Methods