Histological Features Associated With Human Mpox Virus Infection in 2022 Outbreak in a Nonendemic Country
Faris Chalali, M. Merlant, Audrey Truong, Jade Ghosn, Bao-Chau Phung, Bastien Mollo, Ségolène Perrineau, Mayda Rahi, Nadhira Fidouh-Houhou, Valentine Marie Ferré, F. Brunet‐Possenti, V. Descamps, F. Bouscarat, Yazdan Yazdanpanah, Lydia Deschamps, C. Bertin
Abstract
Skin histology of papules and pustules from 5 men having sex with men with mpox infection showed viral intracytoplasmic cytopathic changes, interface dermatitis, marked inflammatory dermic infiltrate including superficial neutrophils and perivascular and periadnexal deep lymphocytes. Histologic description of mpox lesions improves our understanding about clinical presentations and may have some therapeutic implications.
Topics & Concepts
MedicineHistologyOutbreakPathologyCytopathic effectVirusDermatologyImmunologyPoxvirus research and outbreaksBacillus and Francisella bacterial researchHerpesvirus Infections and Treatments