Expectations for the Dual Therapy with Vonoprazan and Amoxicillin for the Eradication of H. pylori
Takahisa Furuta, Mihoko Yamade, Tomohiro Higuchi, Satoru Takahashi, Natsuki Ishida, Shinya Tani, Satoshi Tamura, Moriya Iwaizumi, Yasushi Hamaya, Satoshi Osawa, Ken Sugimoto
Abstract
Vonoprazan (VPZ) inhibits gastric acid secretion more potently than proton pump inhibitors. Recently, attention has been focused on the dual therapy with VPZ and amoxicillin (AMOX) for the eradication of H. pylori. The dual VPZ/AMOX therapy attains the sufficient eradication rate with lowering the risk of adverse events in comparison with the triple therapy and quadruple therapy. Therefore, the dual VPZ/AMOX therapy is considered a useful eradication regimen for H. pylori infection.
Topics & Concepts
MedicineAmoxicillinRegimenInternal medicineDual (grammatical number)GastroenterologyAdverse effectHelicobacter pyloriCure rateMicrobiologyAntibioticsArtBiologyLiteratureHelicobacter pylori-related gastroenterology studiesMicrobial Metabolites in Food BiotechnologyGastroesophageal reflux and treatments