Self-renewal or quiescence? Orchestrating the fate of mesenchymal stem cells by matrix viscoelasticity via PI3K/Akt-CDK1 pathway
Chuanchuan Lin, Ye He, Qian Feng, Kun Xu, Zhe Chen, Bailong Tao, Xuemin Li, Zengzilu Xia, Hong Jiang, Kaiyong Cai
Topics & Concepts
Mesenchymal stem cellSelf-healing hydrogelsStress relaxationMaterials scienceCell biologyViscoelasticityExtracellular matrixMatrix (chemical analysis)BiophysicsStem cellPI3K/AKT/mTOR pathwayProtein kinase BBiomedical engineeringSignal transductionBiologyMedicineComposite materialPolymer chemistryCreepCellular Mechanics and InteractionsMesenchymal stem cell research3D Printing in Biomedical Research