Shortwave infrared fluorescence imaging of peripheral organs in awake and freely moving mice
Bernardo A. Arús, Emily D. Cosco, Joycelyn Yiu, Ilaria Balba, Thomas S. Bischof, Ellen M. Sletten, Oliver T. Bruns
Abstract
basic and pre-clinical research. Accordingly, imaging methods which preclude invasiveness, anesthesia, and/or physical restraint enable more physiologically relevant biological data extraction by eliminating these extrinsic confounders. In this article, we discuss the recent development of shortwave infrared (SWIR) fluorescent imaging to visualize peripheral organs in freely-behaving mice, as well as propose potential applications of this imaging modality in the neurosciences.
Topics & Concepts
Modality (human–computer interaction)NeurosciencePeripheralOptical imagingComputer scienceShortwaveBiomedical engineeringMedicinePsychologyOpticsArtificial intelligencePhysicsOperating systemRadiative transferPhotoreceptor and optogenetics researchOptical Imaging and Spectroscopy TechniquesReceptor Mechanisms and Signaling