Silica Nanoparticles Induce Hepatotoxicity by Triggering Oxidative Damage, Apoptosis, and Bax-Bcl2 Signaling Pathway
Bakhta Aouey, Khadija Boukholda, Brahim Gargouri, Harsharan S. Bhatia, Abdelraheim Attaai, Mohamed Kebieche, Michèle Bouchard, Hamadi Fetoui
Topics & Concepts
Downregulation and upregulationOxidative stressApoptosisReactive oxygen speciesLactate dehydrogenaseHepatocyteChemistryAntioxidantLiver injuryHepatoprotectionSignal transductionPharmacologyBiochemistryBiologyEnzymeGlutathioneGeneIn vitroNanoparticles: synthesis and applicationsHeavy Metal Exposure and ToxicitySelenium in Biological Systems