Reconstituting gut microbiota-colonocyte interactions reverses diet-induced cognitive deficits: The beneficial of <i>eucommiae cortex</i> polysaccharides
Mengli Wang, Penghao Sun, Xuejun Chai, Yongxin Liu, Luqi Li, Wei Zheng, Shulin Chen, Xiaoyan Zhu, Shanting Zhao
Abstract
overgrowth, are a likely cause of HFD-induced cognitive deficits. Furthermore, dietary supplementation with EPs can rectify behavioral dysfunctions associated with HFD by modifying gut microbiota-colonocyte interactions. These insights contribute to the broader understanding of the modulatory effects of plant prebiotics on the microbiota-gut-brain axis and suggest a potential therapeutic avenue for diet-associated cognitive dysfunction.
Topics & Concepts
PolysaccharideGut floraPrefrontal cortexCognitionFood scienceBiologyPhysiologyPsychologyNeuroscienceBiochemistryGut microbiota and healthDiet and metabolism studiesTryptophan and brain disorders