Microglia Do Not Take Up Soluble Amyloid-beta Peptides, But Partially Degrade Them by Secreting Insulin-degrading Enzyme
Hongjun Fu, Bin Liu, Liangping Li, Cynthia A. Lemere
Topics & Concepts
MicrogliaInsulin-degrading enzymeIn vivoInsulinChemistryAmyloid betaIntegrin alpha MBiochemistryEnzymePharmacologyEndocrinologyInternal medicineMedicineBiologyPeptideInflammationCellBiotechnologyAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and Treatments