Recognition of lipoproteins by scavenger receptor class A members
Chen Cheng, Enlin Zheng, Bowen Yu, Ze Zhang, Yuanyuan Wang, Yingbin Liu, Yongning He
Abstract
-independent manner. SCARA3, which does not have a globular domain at the C terminus, was found to have no detectable binding with these lipoproteins. Taken together, these results provide mechanistic insights into the interactions between SR-A family members and lipoproteins that may help us understand the roles of SR-A receptors in lipid transport and related diseases such as atherosclerosis.
Topics & Concepts
Scavenger receptorReceptorLipoproteinBiochemistryLDL receptorApolipoprotein BLow-density lipoproteinChemistryGlycoproteinTransmembrane proteinScavengerTransmembrane domainCell biologyBiologyCholesterolRadicalAtherosclerosis and Cardiovascular DiseasesCholesterol and Lipid MetabolismLipid Membrane Structure and Behavior