Litcius/Paper detail

Advances on the Role and Applications of Interleukin-1 in Tuberculosis

Diogo Silvério, Rute Gonçalves, Rui Appelberg, Margarida Saraiva

2021mBio51 citationsDOIOpen Access PDF

Abstract

, together with a deep understanding of how host-M. tuberculosis interactions modulate IL-1, is required. Here, we discuss the most recent advances in the biology and therapeutic potential of IL-1 in TB as well as the outstanding questions that remain to be answered.

Topics & Concepts

TuberculosisMycobacterium tuberculosisImmune systemImmunologyDiseaseInflammationBiologyMedicineHost responseInfectious disease (medical specialty)Host (biology)Computational biologyAction (physics)ImmunityHost resistanceInflammatory responseBioinformaticsTuberculosis vaccinesSystems biologyGeneHuman diseaseTuberculosis Research and EpidemiologyDiverse Scientific Research StudiesInflammation biomarkers and pathways