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Using Hawkes Processes to model imported and local malaria cases in near-elimination settings

H. Juliette T. Unwin, Isobel Routledge, Seth Flaxman, Marian-Andrei Rizoiu, Shengjie Lai, Justin M Cohen, Daniel J. Weiss, Swapnil Mishra, Samir Bhatt

2021PLoS Computational Biology25 citationsDOIOpen Access PDF

Abstract

Developing new methods for modelling infectious diseases outbreaks is important for monitoring transmission and developing policy. In this paper we propose using semi-mechanistic Hawkes Processes for modelling malaria transmission in near-elimination settings. Hawkes Processes are well founded mathematical methods that enable us to combine the benefits of both statistical and mechanistic models to recreate and forecast disease transmission beyond just malaria outbreak scenarios. These methods have been successfully used in numerous applications such as social media and earthquake modelling, but are not yet widespread in epidemiology. By using domain-specific knowledge, we can both recreate transmission curves for malaria in China and Eswatini and disentangle the proportion of cases which are imported from those that are community based.

Topics & Concepts

MalariaOutbreakTransmission (telecommunications)Computer scienceChinaInfectious disease (medical specialty)Disease transmissionDomain (mathematical analysis)Operations researchData scienceEconometricsRisk analysis (engineering)DiseaseGeographyVirologyBiologyBusinessEconomicsTelecommunicationsMedicineEngineeringImmunologyMathematicsArchaeologyMathematical analysisPathologyPoint processes and geometric inequalitiesDiffusion and Search DynamicsRangeland Management and Livestock Ecology
Using Hawkes Processes to model imported and local malaria cases in near-elimination settings | Litcius