Low MGMT digital expression is associated with a better outcome of IDH1 wildtype glioblastomas treated with temozolomide
Isabella Gomes, Daniel Antunes Moreno, Mariana Bisarro dos Reis, Luciane Sussuchi da Silva, Letícia Ferro Leal, Gisele Melo Gonçalves, Caio Augusto Pereira, Marco Antônio de Oliveira, Marcus Matsushita, Rui Manuel Reis
Topics & Concepts
TemozolomideMethylationATRXO-6-methylguanine-DNA methyltransferaseIDH1MethyltransferaseCancer researchDNA methylationBiologyOncologyMedicineGene expressionGliomaGeneGeneticsMutationGlioma Diagnosis and TreatmentBrain Metastases and TreatmentHedgehog Signaling Pathway Studies