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GJB2 gene therapy and conditional deletion reveal developmental stage-dependent effects on inner ear structure and function

Jingying Guo, Xiaobo Ma, Jennifer Skidmore, Jelka Cimerman, Diane M. Prieskorn, Lisa A. Beyer, Donald L. Swiderski, David F. Dolan, Donna M. Martin, Yehoash Raphael

2021Molecular Therapy — Methods & Clinical Development47 citationsDOIOpen Access PDF

Abstract

-related deafness.

Topics & Concepts

Inner earFunction (biology)Stage (stratigraphy)BiologyDevelopmental stageGenetic enhancementGeneGeneticsNeurosciencePsychologyDevelopmental psychologyPaleontologyHearing, Cochlea, Tinnitus, GeneticsConnexins and lens biologyNeuroscience of respiration and sleep