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Database resources of the National Center for Biotechnology Information

Eric W Sayers, Jeffrey Beck, Evan Bolton, Devon Bourexis, J. Rodney Brister, Kathi Canese, Donald C. Comeau, Kathryn Funk, Sunghwan Kim, William Klimke, Aron Marchler‐Bauer, Melissa Landrum, Stacy Lathrop, Zhiyong Lu, Thomas Madden, Nuala A. O’Leary, Lon Phan, Sanjida H Rangwala, Valérie Schneider, Yuri Skripchenko, Jiyao Wang, Jian Ye, Barton W Trawick, Kim D. Pruitt, Stephen T. Sherry

2020Nucleic Acids Research1,015 citationsDOIOpen Access PDF

Abstract

The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed® database of citations and abstracts published in life science journals. The Entrez system provides search and retrieval operations for most of these data from 34 distinct databases. The E-utilities serve as the programming interface for the Entrez system. Custom implementations of the BLAST program provide sequence-based searching of many specialized datasets. New resources released in the past year include a new PubMed interface and NCBI datasets. Additional resources that were updated in the past year include PMC, Bookshelf, Genome Data Viewer, SRA, ClinVar, dbSNP, dbVar, Pathogen Detection, BLAST, Primer-BLAST, IgBLAST, iCn3D and PubChem. All of these resources can be accessed through the NCBI home page at https://www.ncbi.nlm.nih.gov.

Topics & Concepts

GenBankRefSeqDatabasePubChemBiologyBiological databaseUniProtdbSNPInterface (matter)Online databaseWorld Wide WebBioinformaticsComputer scienceGenomeComputational biologyGeneticsSingle-nucleotide polymorphismGenotypeGenePulmonary surfactantGibbs isothermBiochemistryGenetics, Bioinformatics, and Biomedical ResearchGenomics and Phylogenetic StudiesGene expression and cancer classification
Database resources of the National Center for Biotechnology Information | Litcius