Peroxidation of 3,4-dihydro-1,4-benzoxazin-2-ones
Jie Wang, Xiazhen Bao, Jiayuan Wang, Congde Huo
Abstract
The sp<sup>3</sup>-C–H peroxidation of 3,4-dihydro-1,4-benzoxazin-2-ones was achieved. C(sp<sup>3</sup>)–OO bond could be further converted into C(sp<sup>3</sup>)–C(sp<sup>3</sup>), C(sp<sup>3</sup>)–C(sp<sup>2</sup>), C(sp<sup>3</sup>)–C(sp), C–P and CO bond by late stage functional group transformations.
Topics & Concepts
ChemistryStereochemistryMedicinal chemistryCrystallographyOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization MethodsPhenothiazines and Benzothiazines Synthesis and Activities