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Chemogenetic Seizure Control with Clozapine and the Novel Ligand JHU37160 Outperforms the Effects of Levetiracetam in the Intrahippocampal Kainic Acid Mouse Model

Jana Desloovere, Paul Boon, Lars Emil Larsen, Marie‐Gabrielle Goossens, Jean Delbeke, Evelien Carrette, Wytse J. Wadman, Kristl Vonck, Robrecht Raedt

2021Neurotherapeutics25 citationsDOIOpen Access PDF

Topics & Concepts

Kainic acidLevetiracetamEpilepsyHippocampusClozapinePharmacologyExcitatory postsynaptic potentialHippocampal formationInhibitory postsynaptic potentialNeuroscienceMedicineAnesthesiaReceptorChemistryInternal medicinePsychologyGlutamate receptorSchizophrenia (object-oriented programming)PsychiatryNeuroscience and Neuropharmacology ResearchEpilepsy research and treatmentReceptor Mechanisms and Signaling
Chemogenetic Seizure Control with Clozapine and the Novel Ligand JHU37160 Outperforms the Effects of Levetiracetam in the Intrahippocampal Kainic Acid Mouse Model | Litcius