Papaverine, a Phosphodiesterase 10A Inhibitor, Ameliorates Quinolinic Acid-Induced Synaptotoxicity in Human Cortical Neurons
Abid Bhat, Vanessa Tan, Benjamin Heng, Sharron Chow, Salundi Basappa, Musthafa Mohamed Essa, Saravana Babu Chidambaram, Gilles J. Guillemin
Topics & Concepts
CREBQuinolinic acidNeuroprotectionExcitotoxicityPDE10APharmacologyChemistryBiologyCell biologyPhosphodiesteraseBiochemistryProgrammed cell deathApoptosisTranscription factorGeneEnzymeTryptophanAmino acidPhosphodiesterase function and regulationCholinesterase and Neurodegenerative DiseasesNeuroscience and Neuropharmacology Research