Activation of Nrf2 signaling by oltipraz inhibits death of human macrophages with mycobacterium tuberculosis infection
Qin Sun, Xiaona Shen, Jun Ma, Hai Lou, Qing Zhang
Topics & Concepts
KEAP1MacrophageCytoprotectionApoptosisCytotoxicityReactive oxygen speciesProgrammed cell deathBiologyKnockout mouseMycobacterium tuberculosisCRISPRCell biologyChemistryMicrobiologyTuberculosisBiochemistryGeneIn vitroMedicinePathologyTranscription factorGenomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor AgentsPharmacological Effects of Natural Compounds