S2k guidelines for the diagnosis and treatment of herpes zoster and postherpetic neuralgia
Gerd Gross, Lisa Eisert, Hans Wilhelm Doerr, Helmut Fickenscher, Markus Knuf, Philip Maier, Matthias Maschke, Rainer Müller, Uwe Pleyer, Michael Schäfer, Cord Sunderkötter, Ricardo Niklas Werner, Peter Wutzler, Alexander Nast
Abstract
The present guidelines are aimed at residents and board-certified specialists in the fields of dermatology, ophthalmology, ENT, pediatrics, neurology, virology, infectious diseases, anesthesiology, general medicine and any other medical specialties involved in the management of patients with herpes zoster. They are also intended as a guide for policymakers and health insurance funds. The guidelines were developed by dermatologists, virologists, ophthalmologists, ENT physicians, neurologists, pediatricians and anesthesiologists/pain specialists using a formal consensus process (S2k). Readers are provided with an overview of the clinical and molecular diagnostic workup, including antigen detection, antibody tests and viral culture. Special diagnostic situations and complicated disease courses are discussed. The authors address general and special aspects of antiviral therapy for herpes zoster and postherpetic neuralgia. Furthermore, the guidelines provide detailed information on pain management including a schematic overview, and they conclude with a discussion of topical treatment options.