Structure-activity relationship and mechanism of flavonoids on the inhibitory activity of P-glycoprotein (P-gp)-mediated transport of rhodamine123 and daunorubicin in P-gp overexpressed human mouth epidermal carcinoma (KB/MDR) cells
Yajing Fang, Fuqiang Liang, Mengmeng Xia, Weiwei Cao, Siyi Pan, Ting Wu, Xiaoyun Xu
Topics & Concepts
P-glycoproteinVerapamilDaunorubicinMultiple drug resistancePharmacologyChemistryFlavonoidKaempferolGalanginBiochemistryBiologyImmunologyLeukemiaCalciumOrganic chemistryAntioxidantAntibioticsDrug Transport and Resistance MechanismsCancer therapeutics and mechanismsInflammatory mediators and NSAID effects