THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development
Jiali Zhang, Zhenzhou Jiang, Xueyuan Zhang, Ziqun Yang, Jinjiao Wang, Jialing Chen, Li Chen, Minfang Song, Yanchun Zhang, Mei Huang, Shengmiao Chen, Xuexue Xiong, Yuetong Wang, Piliang Hao, Tiffany Horng, Min Zhuang, Liye Zhang, Erwei Zuo, Fang Bai, Jie Zheng, Haopeng Wang, Gaofeng Fan
Topics & Concepts
PhosphorylationCell biologyAllosteric regulationPhosphataseT-cell receptorActivator (genetics)BiologyT cellSignal transductionReceptorChemistryBiochemistryImmune systemImmunologyProtein Tyrosine PhosphatasesT-cell and B-cell ImmunologyUbiquitin and proteasome pathways