Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors
Zeng Hou, Wenjian Min, Rukang Zhang, Ao Niu, Yuan‐Qing Li, Liyuan Cao, Jie Han, Cheng Luo, Peng Yang, Hong Ding
Topics & Concepts
ChemistryMethyltransferaseEpigeneticsHistone H3Histone methyltransferaseHistoneMethylationLead compoundBiochemistryCancer researchIn vitroBiologyGeneEpigenetics and DNA MethylationCancer-related gene regulationRNA modifications and cancer