In a Rat Model of Opioid Maintenance, the G Protein–Biased Mu Opioid Receptor Agonist TRV130 Decreases Relapse to Oxycodone Seeking and Taking and Prevents Oxycodone-Induced Brain Hypoxia
Jennifer M. Bossert, Eugene A. Kiyatkin, Hannah Korah, Jennifer K. Hoots, Anum Afzal, David Perekopskiy, Shruthi A. Thomas, Ida Fredriksson, Bruce E. Blough, S. Stevens Negus, David H. Epstein, Yavin Shaham
Topics & Concepts
OxycodoneOpioidBuprenorphineAgonistContext (archaeology)AnesthesiaPharmacologyMedicineOpioid receptorHeroinMethadoneSelf-administrationPsychologyInternal medicineReceptorBiologyDrugPaleontologyNeurotransmitter Receptor Influence on BehaviorPain Mechanisms and TreatmentsNeuropeptides and Animal Physiology