pH-Sensitive doxorubicin delivery using zinc oxide nanoparticles as a rectified theranostic platform: <i>in vitro</i> anti-proliferative, apoptotic, cell cycle arrest and <i>in vivo</i> radio-distribution studies
Mohamed M. Swidan, F. A. Marzook, Tamer M. Sakr
Abstract
An innovative pH-responsive and biocompatible agent (Tc-99m labelled DOX-loaded ZnO@dextran) is developed as an intelligent platform for tumor-targeted theranostic applications.
Topics & Concepts
In vivoApoptosisIn vitroMaterials scienceZincNanoparticleDoxorubicinNanotechnologyChemistryMedicineBiologyBiochemistryChemotherapyInternal medicineMetallurgyBiotechnologyNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsGraphene and Nanomaterials Applications