Immune responses to retinal gene therapy using adeno-associated viral vectors – Implications for treatment success and safety
Kirsten Bucher, Eduardo Rodríguez‐Bocanegra, Daniyar Dauletbekov, Manuel Fischer
Topics & Concepts
Genetic enhancementImmune systemImmunologyBiologyAdeno-associated virusViral vectorRetinal degenerationTransgeneVector (molecular biology)Vectors in gene therapyRetinalGene deliveryRPE65InflammationInnate immune systemRetinaVirologyRecombinant DNAGeneNeuroscienceGeneticsBiochemistryVirus-based gene therapy researchRetinal Development and Disordersinterferon and immune responses