Efficient Genome Editing Achieved via Plug-and-Play Adenovirus Piggyback Transport of Cas9/gRNA Complex on Viral Capsid Surface
Zhi Hong Lu, Jie Li, Igor P. Dmitriev, Elena A. Kashentseva, David T. Curiel
Abstract
gene editing.
Topics & Concepts
CapsidCRISPRGenome editingCas9Guide RNAVirologyGenomePlug and playComputational biologyCell biologyHEK 293 cellsBiologyVirusGeneticsComputer scienceGeneOperating systemCRISPR and Genetic EngineeringRNA Interference and Gene DeliveryVirus-based gene therapy research